A recombinant fusion peptide produced in a tobacco-related plant, used as a hair- and skin-conditioning ingredient.
What it is
Nicotiana benthamiana octapeptide-30 sh-oligopeptide-2 is, according to CosIng, a fusion of octapeptide-30 with a single-chain recombinant human peptide, produced by the plant Nicotiana benthamiana after introduction of a copy of a human gene. The starting gene codes for insulin-like growth factor 1 (IGF-1), and the fusion peptide contains 68 amino acids. CosIng lists it as a hair-conditioning and skin-conditioning agent.
Where it is used
Found in hair care and scalp care products.
Limits of interpretation
The INCI list shows which ingredients are present, not how much of each. Above 1%, ingredients are listed in descending order of weight; below 1% the order is free.
The label does not show the concentration of the peptide in the finished product.
Functions
- Hair conditioning
- Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
- Skin conditioning – miscellaneous
- Enhancing the appearance of dry and/or damaged skin by reducing flaking and restoring suppleness.
EU regulation
This ingredient is not listed in the annexes of Regulation (EC) No 1223/2009 in the CosIng data.

