A recombinant human collagen-type peptide produced by fermentation, used as a film former and skin-conditioning ingredient.
What it is
sh-Polypeptide-121 is a single-chain recombinant peptide produced by fermentation in E. coli from a synthesised gene identical to the human gene coding for the collagen alpha-1(XXI) chain. The prefix sh stands for synthetic human. It contains up to 957 amino acids. CosIng lists it as a film-forming and skin-conditioning ingredient.
Where it is used
Found in serums, creams, ampoules and masks.
Limits of interpretation
The INCI list shows which ingredients are present, not how much of each. Above 1%, ingredients are listed in descending order of weight; below 1% the order is free.
Although the sequence is based on a human gene, the ingredient is produced by microbial fermentation and is not taken from human tissue.
Functions
- Film forming
- Producing (upon application) a continuous film on the skin, hair or nails.
- Skin conditioning
- Maintaining the skin in good condition.
EU regulation
This ingredient is not listed in the annexes of Regulation (EC) No 1223/2009 in the CosIng data.
Products with this ingredient (7)
- Vegan Collagen Serum in Foundation SPF30 · Lumene
- Pro-Collagen Peptide Booster Serum · Paula's Choice
- Pro-Collagen Multi-Peptide Booster Serum · Paula's Choice
- Dove Damage Therapy Volume Boost + Collagen Shampoo 350mL · Unilever
- Dove Damage Therapy Volume Boost + Collagen Conditioner 350mL · Unilever
- Dove Damage Therapy Volume Boost & Collagen Shampoo 850mL · Unilever
- Dove Damage Therapy Volume Boost + Collagen Conditioner 850mL · Unilever

