A recombinant human peptide produced in bacteria, listed as a skin-conditioning ingredient.
What it is
sh-Polypeptide-22 is, according to CosIng, a single-chain recombinant human peptide produced by fermentation in the bacterium E. coli. The gene used is synthesised to be identical to the human gene coding for transforming growth factor beta 1 (TGF-beta 1), and the peptide contains up to 390 amino acids. CosIng lists it as a skin-conditioning ingredient.
Where it is used
Appears on the ingredient lists of a small number of products.
Limits of interpretation
The INCI list shows which ingredients are present, not how much of each. Above 1%, ingredients are listed in descending order of weight; below 1% the order is free.
The prefix sh in the INCI name marks a peptide made to be identical to a human sequence; the name does not show how much is used.
Functions
- Skin conditioning
- Maintaining the skin in good condition.
EU regulation
This ingredient is not listed in the annexes of Regulation (EC) No 1223/2009 in the CosIng data.

