A recombinant fusion peptide produced in a plant, listed as a skin-conditioning ingredient.
What it is
Nicotiana benthamiana hexapeptide-40 sh-polypeptide-47 is a fusion peptide of hexapeptide-40 with a single-chain recombinant human peptide, produced by the plant Nicotiana benthamiana, a relative of tobacco, after genetic transformation. According to CosIng, whose monograph for this name is still under development, the starting gene is synthesised to be identical to the human gene coding for collagen alpha-1, and the fusion peptide contains 116 amino acids. CosIng lists it as a skin-conditioning ingredient.
Where it is used
Appears on the ingredient lists of a small number of products.
Limits of interpretation
The INCI list shows which ingredients are present, not how much of each. Above 1%, ingredients are listed in descending order of weight; below 1% the order is free.
The prefix sh in the INCI name marks a peptide made to be identical to a human sequence; the name does not show how much is used.
Functions
- Skin conditioning – miscellaneous
- Enhancing the appearance of dry and/or damaged skin by reducing flaking and restoring suppleness.
EU regulation
This ingredient is not listed in the annexes of Regulation (EC) No 1223/2009 in the CosIng data.
Products with this ingredient (7)
- Collagen-Peptide Lifting And Rejuvenating Routine · BABOR
- Derma Filler Serum · BABOR
- Collagen-Peptide Booster Cream Rich · BABOR
- Travel Size Derma Filler Serum · BABOR
- Travel Size Collagen-Peptide Booster Cream · BABOR
- Collagen-Peptide Booster Cream · BABOR
- Hairification H24 Complex Leave-in Hair Mask 50mL · Hairification

